AgelessRx vs Pepti
Updated October 16, 2026
Adults looking for peptide or longevity care online usually land on AgelessRx or Pepti, two cash-pay telehealth services that ship compounded prescriptions to the door. The part many shoppers skip is that the two are built for different goals: AgelessRx sells clinician-guided aging protocols, while Pepti runs a broad peptide catalog with all-in monthly prices. Because neither sells FDA-approved finished drugs for most of these treatments, the way each prices and reviews care matters more than the product list.
Our analysts compared AgelessRx and Pepti on published prices, physician review, state access, pharmacy and shipping, and catalog focus, using the HIR review of each company and prices checked on each vendor's site. In the following sections, we compare them row by row, describe the shopper each one serves, and note what each has launched in recent months.
AgelessRx vs Pepti at a glance, October 2026
| What buyers weigh | AgelessRx | Pepti |
|---|---|---|
| Published price | As of Sep 2026, starting prices on AgelessRx's treatment pages ran from about $25 per month for drugs such as metformin and low-dose naltrexone. Microdosing tirzepatide started at $159 per month, and sermorelin at $99 for the first month and $149 after that on a 3-month plan. Women's hormone care listed a $50 per month membership plus the cost of medication. Confirm current prices. | Pepti lists $99-$369 per month all-in for prescription peptide treatments (medicine, physician care, and shipping, with no membership fee). Semaglutide starts at $99 per month and tirzepatide at $159 per month at starting doses (as of Sep 2026). Confirm the current price. |
| Pricing model | Online consultations and medication programs sold directly to patients, often with refills on a membership plan. | Consumer programs with one price for the visit and the medicine. |
| What drives cost | Which program you join, how your dose is adjusted, any required lab tests, shipping, and membership or follow-up fees. | Which treatment and dose, optional at-home labs, and dose increases approved by the physician, billed at pharmacy cost. Pepti posts full monthly prices with no membership fee. |
| Main job | Longevity-oriented telehealth with peptide and related protocols. | Peptide and specialty medication telehealth with published all-in monthly prices. |
| Getting care in your state | Scores 7.6. | Scores 8.2. Higher score |
| Physician review | Scores 7.4. | Scores 8.0. Higher score |
| Pharmacy and shipping | Scores 7.0. | Scores 7.6. Higher score |
| Price clarity | Membership-style refills; scores 6.9 on knowing what you will pay. | Publishes all-in monthly prices with no membership fee; scores 7.4. Higher score |
| Catalog focus | Smaller DTC longevity platform with clinician-guided protocols. | Wider peptide, weight, muscle, and anti-aging style offerings through one front door. Clear edge |
| What you need first | Interest in longevity or peptide programs guided by a clinician over telehealth. | Living in a U.S. state where the physicians and pharmacy partners can serve you. |
| Deal-breaker | You treat compounded or off-label longevity therapies as if they were FDA-approved for anti-aging claims. | You only want finished FDA-approved drugs and will not accept compounded options. |
| Pricing clarity score | 6.9 | 7.4 Clearer pricing |
| HIR overall score | 7.3, Recommend. | 7.9, Recommend. Higher score |
| Best for | Consumers comparing smaller DTC longevity platforms that include clinician-guided peptide and related programs. | Consumers comparing LegitScript-certified peptide telehealth with licensed physician access. |
| Not a fit for | Anyone treating compounded or off-label longevity therapies as if they were FDA-approved for anti-aging claims. | Anyone treating compounded medications as if they were FDA-approved finished drugs. |
Which fits which buyer
Pick by what you want treated and how much you care about one predictable bill.
Choose AgelessRx if
- You want a longevity protocol, such as metformin or low-dose naltrexone, guided by a clinician who focuses on aging.
- You like a company that runs its own aging research and publishes results.
- You are comfortable with a membership-style refill plan.
Choose Pepti if
- You want one all-in monthly price that covers the medicine, the physician, and shipping.
- You want weight, recovery, skin, and hormone peptides from a single account.
- You want a fast physician review with no membership fee.
Verdict
Pepti is the stronger pick for most peptide shoppers, with higher marks on state access, physician review, and price clarity. AgelessRx suits someone whose real interest is an aging protocol designed by clinicians who study longevity.
Skip both if you need FDA-approved finished drugs or an in-person specialist.
Where the two tools are headed in 2027 and beyond
AgelessRx: AgelessRx added PT-141 in injectable and nasal spray forms in August 2026, then launched compounded methylene blue capsules and a prescription GHK-Cu copper peptide cream in October 2026. Its research team was named a Milestone 2 awardee in the XPRIZE Healthspan competition in August 2026.
Before you subscribe to either, ask for the full price at your expected dose for three months, including any labs.
Methodology
Each row comes from the HIR reviews of AgelessRx and Pepti, scored under the HIR method, and from each vendor's public pricing where it exists. Any published price for AgelessRx or Pepti was checked on that vendor's own site on October 16, 2026.
A green check marks a clear edge for AgelessRx or Pepti only where their review scores differ by at least 0.3 points or the two reviews show a plain difference. Rows with nothing published for either AgelessRx or Pepti are left out, and time to full value for each adds up the rollout stages in its review.
Sources
- HIR review of AgelessRx and HIR review of Pepti
- AgelessRx pricing, checked October 16, 2026
- Pepti pricing, checked October 16, 2026
- AgelessRx launches methylene blue, October 2026
- AgelessRx XPRIZE Healthspan update, October 2026