Company leader
Carolyn Lam
Co-founder
Us2.ai
Carolyn Lam is a cardiologist at the National Heart Centre Singapore, a professor at Duke-NUS Medical School, and a co-founder of Us2.ai, whose AI software analyzes heart ultrasound scans. She is one of the leading researchers on heart failure with preserved ejection fraction, a common form of heart failure that long had no approved treatment.
Training as a Cardiologist
Lam earned her medical degree at the National University of Singapore in 1998. She then trained in heart failure and advanced cardiology at Mayo Clinic in Rochester, Minnesota, and in clinical and genetic epidemiology at the Framingham Heart Study, finishing that fellowship in 2010. She completed the Stanford Executive Programme in 2015 and earned a PhD from the University Medical Centre Groningen in the Netherlands in 2016.
Leading Heart Failure Research
Her work on the PARAGON-HF and EMPEROR-Preserved trials led to the first FDA-approved treatment for this form of heart failure and to the first strongly positive outcomes trial in it. She has published hundreds of papers in journals including the New England Journal of Medicine, JAMA, and The Lancet, and she is the lead author of the chapter on the condition in Braunwald's Heart Disease, a standard cardiology textbook.
She led ASIAN-HF, a study across 11 Asian countries, and in 2019 started the Asian Diabetes Outcomes Prevention Trial. She also set up Singapore's first Women's Heart Clinic and sat on the European Society of Cardiology task force that wrote its 2021 heart failure guidelines.
Co-founding Us2.ai
In 2017 Lam co-founded the company that became Us2.ai with her husband, James Hare, and the researcher Yoran Hummel, and she serves as its medical lead. At the National Heart Research Institute Singapore she has been scientific lead for echo imaging since 2021.
Family and Public Life
Lam lives in Singapore with Hare and their son. She can be heard each week on Circulation on the Run, the podcast of the journal Circulation, where she is an associate editor, and she appears on Singapore television as the resident doctor of the MediaCorp health program Body and Soul.